Welcome to the Horomone Receptor Target Binding Loci Database (HRTBLDb). The HRTBLDb is a collection of estrogen, androgen, and glucocorticoid receptor binding site data.
The publication concerning this database and web service has been published by Nucleic Acids Research! It is titled
"HRTBLDb: an informative data resource for Hormone Receptors Target Binding Loci."
(Full Article) Cite this database as
HRTBLDb: an informative data resource for hormone receptors target binding loci
Brian A. Kennedy; Wenqing Gao; Tim H.-M. Huang; Victor X. Jin
Nucleic Acids Research 2009; doi: 10.1093/nar/gkp734
Data from high through-put lab techniques (ChIP-chip, ChIP-Seq, and ChIP-PET) are integrated in to this unified database to aid research on the hormone signaling pathways that regulate gene expression. Hormone induced differential gene expression has been implicated in numerous pathological conditions. Given this implication, research in hormone receptor binding sites is increasing at a rapid pace, and with the advent of whole genome analysis, the volume of data generated by this research is immense. HRTBLDb is built to help researchers collaborate and prosper from this explosion of data.
You can search the human, mouse, and rat genomes for hormone receptor binding sites
according to multiple criteria. If this is your first time using the site click here to
Direct Binding
Co-occurrent Binding
Indirect Binding